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               MRA

               The non-ionizing radiation modality of MRA
               utilizes gadolinium-based contrast agents to
               provide information on arterial vessel anatomy
               (Russo & Katsicas, 2018). This includes
               characteristics such as edema, thickness, and
               contrast enhancement during stages of
               inflammation (Russo & Katsicas, 2018).
               Sensitivity and specificity of MRA detecting TA
               is 100% (Mavrogenic et al., 2013). Figure 13
               shows narrowing in the left subclavian artery       Figure 13. MRA of a left subclavian artery stenosis. Adapted
               (Mavrogeni et al., 2013). The capability of MRA     from “The role in multimodality imaging in the evaluation of
               to perform cross-sectional arterial wall scans      Takayasu Arteritis” by S. Mavrogeni, T. Dimitroulas, S.N.
               allows for detection of regions of myocardial       Chatziioannou, & G. Kitas, 2013, Seminars in arthritis and
                                                                   rheumatism, 42 (4), p. 409. Copyright [2013] by Seminars in
               infarction, fibrosis, and intramural inflammation   arthritis and rheumatism. Adapted with permission.
               (Russo & Katsicas, 2018; Kissin & Merkel,
               2004). Figure 14a portrays mural thickening and increased diameter of the ascending aorta in the
               axial plane (Gaballah, Goldfisher, & Amodio, 2017). Figure 14b has the axial double inversion
               sequence with the descending aorta diameter measuring at 2.2cm (Gaballah et al., 2017). These
               findings correlate with the areas of dilation and stenosis seen in the DSA images.


























                Figure 14. MRA axial double inversion recovery sequence at the level of the chest and abdomen. A) Mural thickening
                 (arrow) of the ascending aorta. A diameter of 3.4cm is noted. B) Stenotic region of the descending aorta noted with a
                 2.2cm diameter. Adapted from “The utility of MRI in the diagnosis of Takayasu arteritis” by M. Gaballah, R. Goldfisher,
                & J.B. Amodio, 2017, Hindawi Case Reports in Pediatrics, p.3. Copyright [2017] by Hindawi Case Reports in
                Pediatrics. Adapted with permission.
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