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Amlodipine (Norvasc, Istin) Amprolium (Corid) 1463

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Amlodipine (Norvasc, Istin) Hypertension: 0.1-0.5 mg/kg PO Hypertension: 0.625 mg/CAT PO Titrate dose upward as needed Tablets. May be
compounded into a
q 12-24h; titrate up to effect
to reduce risk of anorexia
q 12-24h, or 0.125-0.25 mg/
with maximum dose 1 mg/
kg PO q 24h up to 0.5 mg/kg
and syncope (cats). Gingival
stable oral suspension.
hyperplasia has been reported
kg/day
as needed
in dogs. Hypotension and
bradycardia are possible in dogs
and cats.
Ammonium chloride Urinary acidification: 20 mg/kg Urinary acidification: 20 mg/kg Most common adverse effect is GI Tablets. Compounding
(Uroeze) PO q 8-12h PO q 12h upset. May result in metabolic pharmacies may supply
Intoxication benefiting from acidosis. Contraindicated in metered scoops of bulk
acidification: 50 mg/kg PO patients with uremia or hepatic powder for addition to
q 6h encephalopathy (tolerance test food.
Ammonia tolerance test: 100 mg/ dangerous and not necessary if
kg PO or by enema once fasting ammonia is elevated).
(check fasting ammonia first; if
increased, test should not be
performed)
Amoxicillin (Amoxil, Amoxi- Susceptible infections: Susceptible infections: Most common adverse effect is GI Tablets, capsules, powder
Tabs, Amoxi-Drop) 11-20 mg/kg PO q 8-12h 11-15 mg/kg PO q 8-12h upset. Hypersensitivity reactions for oral suspension
Borreliosis infections: 20 mg/kg have been reported.
PO q 8h for 30 days
Amoxicillin/clavulanic acid Susceptible infections: Susceptible infections: 12.5- Most common adverse effect is GI Tablets, oral suspensions. If
(Clavamox, Augmentin) 12.5-25 mg/kg PO q 8-12h 25 mg/kg PO q 8-12h upset. Hypersensitivity reactions using fractions of tablets,
Staphylococcal endocarditis: Upper respiratory infection: have been reported. Neurotoxicity wrap remainder tightly in
22 mg/kg PO q 8h for 6-8 12.5 mg/kg PO q 12h in dogs has been reported after foil before next use.
weeks use of high doses.
Amphotericin B Susceptible mycotic or algal Susceptible mycotic or algal Some degree of dose-related Injection for reconstitution.
deoxycholate (Fungizone) infections: 0.25-0.5 mg/kg infections: 0.25-0.5 mg/kg nephrotoxicity is inevitable; Do not mix with 0.9 %
diluted in 5% dextrose (final diluted in 5% dextrose to final lipid-complexed and liposome- saline. Some clinicians
concentration ≤0.1 mg/mL) concentration of 0.1 mg/mL encapsulated amphotericin B is diurese with saline before
and give IV over 4 to 6 hours and give IV over 4-6 hours q less nephrotoxic. treatment.
q 48h to total cumulative dose 48h to total cumulative dose
of 8-12 mg/kg or first signs of 6-10 mg/kg or first signs
of nephrotoxicosis. Alternative of nephrotoxicosis
route of administration is
to dilute dose in 500 mL of
0.45% saline/2.5% dextrose
(<20 mg/liter concentration) for
SQ administration q 48h
Amphotericin B liposomal Susceptible mycotic or algal Susceptible mycotic or algal Lipid-complexed and liposome- Injection for reconstitution.
encapsulated (AmBisome, infections: 1-3.3 mg/kg diluted infections: 1 mg/kg diluted encapsulated amphotericin Dilute calculated dose in
Abelcet) (≤1 mg/mL) in D 5W given IV (≤1 mg/mL) in D 5W given IV B is less nephrotoxic than D 5W to ≤1 mg/mL.
over 2 hours administered q over 2 hours administered q conventional formulation and
48h to total cumulative dose of 48h to total cumulative dose therefore may be used in
12-20 mg/kg or first signs of of 8-12 mg/kg or first signs a higher cumulative dose.
nephrotoxicosis of nephrotoxicosis However, infusion reactions such
as phlebitis are more common.
Ampicillin (Princillin, Susceptible infections: Susceptible infections: Adverse events are usually Injection, capsules.
Omnipen, Polyflex) 20-40 mg/kg IV q 6-8h. Higher 20-40 mg/kg IV q 6-8h. GI; hypersensitivity has Amoxicillin is preferred
dosages required for many Higher dosages required for been reported. Many dosing over ampicillin for oral
enterococcal infections. many enterococcal infections. references to IV ampicillin are administration.
appropriate only for ampicillin
sodium solutions for injection.
Ampicillin trihydrate suspension
for injection (Polyflex) should not
be given IV.
Ampicillin + sulbactam Susceptible infections: Susceptible infections: Injections can cause pain (IM Injection
(Unasyn) 20-30 mg/kg IV q 6-8h 20-30 mg/kg IV q 6-8h and SQ) or thrombophlebitis
(IV). Hepatotoxicity has been
reported in humans and
anecdotally observed in dogs.
Hypersensitivity reactions
occasionally reported.
Amprolium (Corid) Coccidiosis: Adults Coccidiosis: 60-100 mg/CAT PO Ensure that patient swallows Oral solution, soluble oral
300-400 mg/DOG PO q 24h q 24h for 7 days entire dose as it is extremely powder
for 7-12 days; puppies 60 to bitter. Prolonged high doses or Drug Compendium
200 mg/PUP PO q 24h overdoses may cause thiamine
deficiency.

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