Page 2804 - Cote clinical veterinary advisor dogs and cats 4th

Capromorelin (Entyce) Cefoxitin 1467

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Capromorelin (Entyce) Appetite stimulant: 3 mg/kg PO Appetite stimulant: 1-3 mg/kg Well tolerated, but can cause GI Oral solution
upset, polydipsia, hypersalivation,
q 24h
PO q 24h for up to 21 days
abdominal discomfort, head
shaking, lethargy, elevated BUN
and phosphorus.
Carboplatin (Paraplatin) Antineoplastic: 300 mg/m IV in Unlike cisplatin, carboplatin Adverse events commonly include Injection; rapidly degrades to
2
D 5W over 15 minutes q 3 weeks may be used in cats. GI toxicity and myelosuppression. cisplatin in saline solutions.
2
for 4 treatments Antineoplastic: 200 mg/m IV In dogs two nadirs occur around Cytotoxic, NIOSH-listed
in D 5W over 15 minutes q 4 day 7-10 and 16-21 post hazardous drug and should
weeks. Carboplatin degrades carboplatin therapy. be prepared, administered,
to cisplatin in saline and disposed of in
solutions. accordance with federal and
local requirements.
Carnitine: see L-carnitine
Carprofen (Rimadyl, Novox, Antiinflammatory/analgesic NSAID: Not recommended for use in Adverse effects commonly include Oral caplets, chewable tablets,
Quellin, Vetprofen) 4.4 mg/kg PO q 24h OR divided cats due to nephrotoxicity. GI upset. Hepatocellular necrosis and injection. Oral liquids may
and given as 2.2 mg/kg PO Not approved for use in cats in occurs in 0.05% of dogs be prepared from tablets.
q 12h USA, but UK label: 4.4 mg/kg treated. Other reported adverse
IV or SQ once effects include neurotoxicity
and hematologic and behavioral
changes.
Carvedilol (Coreg) Valvular heart disease: initial dose Dosing in cats is not described. Use with caution if at all in Tablets, extended-release oral
0.15-0.2 mg/kg PO q 12h dogs with CHF as carvedilol capsules
for 1 week. After evaluating is a negative inotrope. Other
blood pressure and heart rate, side effects include lethargy,
the dose can be increased to inappetence, and hypotension.
0.3 mg/kg PO q 12h.
Cefadroxil (Cefa-Tabs, Susceptible infections: 22 mg/kg Susceptible infections: 22 mg/ Well tolerated, but most common Tablets, capsules, and powder
Cefa-Drops, Duricef) PO q 12h kg PO q 12-24h adverse effect is GI upset. for oral suspension
Superficial pyoderma: 22-35 mg/ Hypersensitivity reactions have
kg PO q 12h for 28-42 days been reported.
Cefazolin sodium (Ancef, Susceptible infections or surgical Susceptible infections or Well tolerated, but adverse effects Injection, injection for
Kefzol) prophylaxis: 22-35 mg/kg IM, surgical prophylaxis: include GI upset and pain on IM reconstitution
IV, SQ q 6-8h. CRI 1.3 mg/ 22-35 mg/kg IM, IV q 8-12h injection. Hypersensitivity occurs
kg loading dose, followed by rarely. Consider dose reduction
1.2 mg/kg/h in advanced renal failure.
Cefotaxime (Claforan) Susceptible infections: 20-80 mg/ Susceptible infections: Generally well tolerated. IM and Injection
kg (often 40 mg/kg) IV, SQ, or 20-80 mg/kg (often 40 mg/ SQ injections may be painful.
IM q 6-12h kg) IV, SQ, or IM q 6-12h Rare adverse effects include
CRI with an initial IV load of CRI with an initial IV load of neurotoxicity, cytopenias,
3.2 mg/kg IV followed by a CRI 3.2 mg/kg IV followed by a hepatitis, and renal damage.
of 5 mg/kg/h CRI of 5 mg/kg/h
GI surgical prophylaxis: 30 mg/kg
IV 30-60 minutes before incision
Cefotetan (Cefotan) Susceptible infections: 30 mg/kg Susceptible infections: 30 mg/ Generally well tolerated. IM and Injection
IV or SQ q 8-12h kg IV or SQ q 8-12h SQ injections may be painful.
GI surgical prophylaxis: 30 mg/kg GI surgical prophylaxis: 30 mg/ Rare adverse effects include
IV 30-60 minutes before incision kg IV 30-60 minutes before neurotoxicity, cytopenias,
incision hepatitis, and renal damage.
Cefovecin (Convenia) Susceptible infections: 8 mg/ Susceptible infections: 8 mg/ Well tolerated but adverse effects Injection for reconstitution
kg SQ once; can be repeated kg SQ once include anorexia, depression, in sterile water; keep
once in 1 to 2 weeks if partial and vomiting. Hypersensitivity refrigerated and protect from
resolution of infection reactions have occurred. light. Reconstituted product
Cefovecin is highly protein bound darkens on storage but can
and should be used cautiously be kept for 2 months.
with other drugs that are highly
bound to plasma proteins.
Cefoxitin Susceptible infections: 30 mg/kg Susceptible infections: 30 mg/ Rare hypersensitivity reactions Injection (powder for
q 6-8h IM or IV kg q 6-8h IM or IV reconstitution or solution).
Presurgical prophylaxis: Presurgical prophylaxis: Once reconstituted, stable for
20-30 mg/kg IV, IM 30 minutes 20-30 mg/kg IV, IM 24 h at room temperature or
before surgery; may repeat in 30 minutes before surgery; up to 1 week if refrigerated.
3-6 h may repeat in 3-6 h Solution can be frozen
immediately once for longer
storage up to 45 days. Drug Compendium

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