Page 2805 - Cote clinical veterinary advisor dogs and cats 4th

1468 Cefpodoxime (Simplicef, Vantin) Chorionic gonadotropin, human (Chorulon, HCG)

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Cefpodoxime (Simplicef, Susceptible skin and soft tissue Susceptible skin and soft tissue Well tolerated but adverse effects Tablets
include inappetence, GI upset,
Vantin)
infections: 5-10 mg/kg PO
infections: 5-10 mg/kg PO q
24h
q 24h
and lethargy. Hypersensitivity and
pemphigus-like drug reactions
are rare, but possible.
Ceftazidime (Ceptaz, Fortaz, Susceptible infections (usually Susceptible infections (usually Painful on IM injection. May Injection
Tazicef) Pseudomonas): 30 mg/kg Pseudomonas): 30 mg/ cause GI upset or dysbiosis.
IV, IM, SQ q 6-8h or as a kg IV, IM, SQ q 8h or as Hypersensitivity has been
continuous IV infusion (CRI) a continuous IV infusion reported.
with a loading dose of 4.4 mg/ (CRI) with a loading dose of
kg and a CRI infusion rate of 4.4 mg/kg and a CRI infusion
4.1 mg/kg/h rate of 4.1 mg/kg/h
Infections other than
Pseudomonas: 30-50 mg/kg IV
or IM q 6-12h
Cephalexin (Keflex, Cepexin, Susceptible infections: 22-40 mg/ Susceptible infections: Well tolerated, but adverse effects Capsules, tablets, powder for
cefalexin) kg PO q 8-12h 15-30 mg/kg PO q 8-12h include GI upset. Hypersensitivity oral suspension
or blood dyscrasias occur rarely.
Consider dose reduction in
advanced renal failure.
Cetirizine (Zyrtec) Antipruritic antihistamine: Antipruritic antihistamine: Generally well tolerated. Sedation, Tablet, oral solution OTC
5-10 mg/DOG (up to maximum 5 mg/CAT PO q 24h hypersalivation and ataxia may
2 mg/kg) PO q 12h occur in animals despite being a
“nonsedating” antihistamine.
Charcoal, activated GI adsorbent for acute poisoning: GI adsorbent for acute Do not administer to animals that Granules and oral suspensions
1-2 g/kg PO or by stomach poisoning: 1-2 g/kg PO or are vomiting (aspiration risk) or combined with sorbitol
tube (preferred); use labeled by stomach tube (preferred); that have ingested caustic or cathartic to encourage
dose when using commercial use labeled dose when using corrosive materials. Charcoal evacuation of charcoal-bound
product. Can be mixed with commercial product. Can combined with cathartic can toxicant
small amount of canned food or be mixed with small amount cause hypernatremia (especially
broth and offered for voluntary of canned food or broth in smaller animals). Rapid
consumption, or mixed with and offered for voluntary administration may cause
water (1 g/5 mL) for syringe or consumption, or mixed with vomiting/aspiration. Not effective
tube administration water (1 g/5 mL) for syringe for all toxicants (e.g., mineral
or tube administration acids or alkalis, ethanol,
fertilizer). Stains clothing.
Chitosan-based phosphate Phosphate binder: 1 g/5 kg BW Phosphate binder: 1 g/5 kg BW Contains lactose, calcium Scoopable powder to add to
binder (Epakitin) PO q 12h PO q 12h carbonate, chitosan, and food
hydrolyzed soy protein.
Chlorambucil (Leukeran) Antineoplastic: 2 mg/m PO q 24h Antineoplastic: 15 mg/m PO Adverse events commonly include Tablets. Cytotoxic, NIOSH-listed
2
2
for 3 weeks beyond remission; q 24h for 4 days, repeated GI toxicity and myelosuppression. hazardous drug and should be
2
then 1.5 mg/m PO q 24h for q 3 weeks, or 2 mg/CAT PO prepared, administered, and
2
15 days and then q third day; or q 48h, or 20 mg/m PO q 2 disposed of in accordance
0.1-0.2 mg/kg PO q 24-72h, or weeks. Often administered with federal and local
15-20 mg/m PO q 2 weeks with prednisolone. requirements. Although can
2
be compounded, advisability
of using compounded liquids
is questionable due to
possible human exposure.
Chloramphenicol (Viceton) Susceptible infections: 40-60 mg/ Susceptible infections: Can cause bone marrow Tablets, capsules, oral
kg PO, IM, IV q 6-8h 15-50 mg/kg PO, IM, IV suppression, as well as GI suspension, injection, and
q 12h upset. Use with extreme caution ophthalmic ointment. Owner
in patients with pre-existing should be cautioned to wear
hematologic disorders, gloves and wash hands after
pregnancy, hepatic failure, and administration.
in neonates. Lower doses used
in cats as they are at higher risk
for adverse events, especially if
used >14 days. Multiple drug
interactions. Risk of aplasia in
humans who are susceptible.
Chorionic gonadotropin, Cryptorchidism: 100-1000 units/DOG Induction of ovulation: 500 Contraindicated in androgen- Injection
human (Chorulon, HCG) IM q 3-4 days × 4 treatments units IM on day 1 or days 1 responsive neoplasias or
Testosterone stimulation for and 2 of estrus. Alternatively, hypersensitivity to the drug.
gonadal status testing: Measure 250 units IM on days 2 and
testosterone before and 24 3 of estrus, coupled with
hours after 750 units IV mating 3 times per day at
(regardless of body weight) 3-hour intervals for the first
Male infertility (controversial): 500- 3 days of estrus.
1000 units/DOG IM q 2 weeks
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