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Chapter 26  Coagulation disorders  /  361




                           in the newborn or with malabsorption) or   consumption of coagulation factors and
                           caused by vitamin K antagonist therapy   platelets.


                           (e.g. warfarin).                           ■    Fresh frozen plasma is used in treatment of

                              ■    Other common coagulation abnormalities   multiple coagulation defects, or specifi c

                           are those in liver disease caused by    defects if the appropriate concentrate is
                           reduced synthesis of coagulation factors   not available, and in therapy for thrombotic
                           and in disseminated intravascular       thrombocytopenic purpura.
                           coagulation (DIC), which causes




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