Page 463 - Essential Haematology

Index / 449

pruritus, Hodgkin lymphoma 246 indices 26–7 reticuloendothelial system 74, 76,
pseudopolycythaemia 203, 208 iron defi ciency 41–2 114
pseudoxanthoma elasticum 331 integrity control 143–4 retina, hyperviscosity syndrome
PTPN11 gene mutation 222 membrane 24–5 285, 286
pulmonary embolism defects 77–9 Rh antibodies 399, 401–2
diagnosis 371 normal values 25, 425 see also haemolytic disease of the
diagnostic imaging 365 oxygen transport 19, 21 newborn
mechanical methods of plasma-depleted 409, 409–10 Rh genes 399, 401
prophylaxis 377 potassium loss 408 Rh genotypes 401, 402
pulmonary hypertension, sickle cell shape/size variation in anaemia fetal Rh D 419
anaemia 100, 102 29 Rh haemolytic disease of the
purpura storage 408 newborn 84, 419,
infection-associated 332 substitutes 410 420–1, 422
post-transfusion 337, 408 for transfusion 408, 409, Rh immunization prevention 419,
purpura fulminans, protein C 409–10 420
defi ciency 367, 418 red cell aplasia 294–5 Rh system 399, 400, 401–2
pyridoxine 47 classifi cation 294 group determination 405
pyrimethamine 63 transient 294, 295 rheumatoid arthritis 385
pyruvate kinase defi ciency 82 red cell fragmentation syndromes rituximab
85 autoimmune neutropenia 120
Q red cell membrane 22, 24 autoimmune thrombocytopenic
5q-syndrome 215, 216 Reed–Sternberg (RS) cells 246 purpura 336
quinidine 337 refractory anaemia 215, 216 CLL 240
quinine 337, 391 with excess blasts 215, 216 cold autoimmune haemolytic
with ring sideroblasts and anaemias 84

R thrombocytosis 47, 192, diffuse large B-cell lymphomas
radiotherapy 215, 216, 221 268
acquired immune defi ciency refractory cytopenia with follicular lymphoma 266
139–40 multilineage dysplasia lymphoplasmacytoid lymphoma
ALL 229, 230 (RCMD) 215, 216 265
CLL 240 refractory neutropenia 215 mechanism of action 265
Hodgkin lymphoma 250 refractory thrombocytopenia 215 post-transplant
multiople myeloma 280 renal allografts 387 lymphoproliferative
RANKL (receptor activator of renal failure diseases 312
nuclear factor-κB ligand) anaemia 385–7 red cell aplasia 294–5
277 coagulation abnormalities 387 thrombotic thrombocytopenic
RARα gene 182, 186 haematological changes 385–7 purpura 338
RAS oncogene mutations 157 iron defi ciency 387 romiplostim, chronic idiopathic
red cell(s) 17, 22, 23, 24–5 multiple myeloma 278, 279, 281 thrombocytopenic
agglutination 404 platelet abnormalities 387 purpura 336
alloantibodies 405 reticulocyte(s) 17 Rosai–Dorfman syndrome 122
alloimmunization 418–19 factors impairing normal rubella, lymphocytosis 390
antigens 398 response to anaemia 28
count in anaemia 25 RNA 30 S
defective metabolism 79–82 reticulocyte count 27–8 S phase of cell cycle 10, 11
destruction 74 iron defi ciency 41–2 saline–adenine–glucose–mannitol
haemoglobin synthesis 20 reticulocytosis, haemolytic anaemia allergic reactions 407
inclusions 30 75 preparation 398