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Intestinal Cestodes   167


                   tapeworm lives in the small intestine and, because the
                   organism is hermaphroditic, it can mate with itself.  After   MICROSCOPIC DIAGNOSTIC
                   self-fertilization occurs, eggs are produced and these un-       FEATURE
                   embryonated eggs leave the human host while contained
                   within the feces. Because no development has occurred
                                                                     General Classification—Cestode (fish
                   until the eggs are released, the egg disintegrates in fresh
                                                                     tapeworm)
                   water and a ciliated embryo called the coracidium is
                   freed into the water where it infects the first intermedi-  Organism   Diphyllobothrium
                   ate host, a copepod crustacean of the genus Cyclops.                     latum “worm”
                   A procercoid larval form develops in the copepod and   Specimen Required  Stool specimen
                   the infected crustacean is eaten by a second intermedi-  Stage         Scolex and proglot-
                   ate host, which is a freshwater fish. If the undercooked               tids are detected;
                   or uncooked freshwater fish is eaten by a human or other               although the egg
                   mammal, infection occurs. A scolex emerges for attach-                 is most commonly
                   ment to the intestinal wall and the tapeworm matures in                detected
                   the small intestine.                              Size                   Worm may reach a
                                                                                          length of up to
                                                                                          10 meters
                   Disease Transmission
                                                                     Shape                Scolex has two sucking
                   Infections with the D. latum organism due to diet are en-              grooves (bothria); pro-
                                                                                          glottid has prominent
                   demic in some parts of the world including Alaska, the
                                                                                          rosette-shaped uterus
                   Great Lakes region, and countries of the Scandanavian
                                                                     Motility               Not demonstrated in
                   peninsula, Latin America, Africa, and Asia where fish is a
                                                                                          D. latum larvae
                   large part of the diet. If the first intermediate host, which
                                                                     Other Features         Proglottid wider
                   is the copepod, is ingested by humans through contami-
                                                                                          than it is long, with a
                   nated water, the procercoid larvae may develop into a
                                                                                            rosette-shaped uterus
                   sparganum, a process called sparganosis, where the lar-
                                                                                          Scolex is 2–3 mm long
                   vae migrate into the human’s subcutaneous tissues.
                                                                                          and is elongated with
                                                                                          two sucking grooves
                   Laboratory Diagnosis                                                   opposite each other
                                                                                          dorsally and ventrally
                                                                      D. latum
                   Proglottids and the scolex of D. latum are seldom found
                   in the examination of human feces. Definitive diagnosis
                   is usually accomplished by detection of the characteristic
                   eggs of D. latum from human feces.
                       Finding the characteristic eggs of D. latum is the
                   most often used diagnostic feature and also enables dif-
                   ferentiation from the eggs of the fluke Paragonimus west-
                   ermanni. This tapeworm egg lacks the “shoulders” near
                   the operculum that are found in fluke eggs.

                   Treatment and Prevention

                   Praziquantel and niclosamide are the drugs of choice for
                   D. latum infections. If a sparganum (larval stage of certain
                   tapeworms, especially of the genera Diphyllobothrium)                                          Delmar/Cengage Learning
                   occurs, surgical removal may be required. Prevention of
                   infection includes avoiding raw or undercooked fish and
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