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13. Siwak DR, Skishodia S, Aggarwal BB, Kurzroch R: Curcumin- 17. Kune GA, Bannerman S, Field B, et al: Diet, alcohol, smoking, serum
induced antiproliferative and proapoptotic effects in melanoma cells beta-carotene, and vitamin A in male nonmelanocytic skin cancer
are associated with suppression of IkappaB kinase and nuclear factor patients and controls. Nutr Cancer 18:237-244, 1992.
KappaB activity and are independent of the B-raf/mifogen- 18. Greenberg ER, Baron JA, Stukel TA, et al: A clinical trial of beta
activated/extracellular signal-regulated protein kinase pathway and carotene to prevent basal-cell and squamous-cell cancers of the
the akt pathway. Cancer 104:879-890, 2005. skin. The Skin Cancer Prevention Study Group. N Engl J Med
14. Clark LC, Combs GF, Turnbull BW, et al: Effects of selenium 323:789-795, 1990.
supplementation for cancer prevention in patients with carcinoma 19. Stryker WS, Stampfer MJ, Stein EA, et al: Diet, plasma levels of
of the skin: A randomized controlled trial. Nutritional Prevention of beta-carotene and alpha-tocopherol, and risk of malignant
Cancer Study Group. JAMA 276:1957-1963, 1996. melanoma. Am J Epidemiol 131:597-611, 1990.
15. Duffield-Lillico AJ, Slate EH, Reid ME, et al: Selenium 20. Miyai E, Yanagida M, Akiyama J, Yamamoto I: Ascorbic acid
supplementation and secondary prevention of nonmelanoma skin 2-O-alpha-glucoside, as table form of ascorbic acid, rescues human
cancer in a randomized trial. J Natl Cancer Inst 95:1477-1481, 2003. keratinocyte cell line, SCC, from cytotoxicity of ultraviolet light B.
16. Wang Z, Boudjelal M, Kang S, et al: Ultraviolet irradiation of human Biol Pharm Bull 19:984-987, 1996.
skin causes functional vitamin A deficiency, preventable by all-trans
retinoic acid pre-treatment. Nat Med 5:418-422, 1999.
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