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5.6




            Adrenal gland


















            The adrenal glands of dogs are bilobed and located cra-  common trunk receives the adrenal veins, which are
            nial and medial to the left and right kidneys. The right   short and not visible on imaging exams. However, they
            adrenal gland is normally in contact with the caudal   do form a point of entry to the vascular system in the
            vena cava on its dorsolateral aspect. The adrenal glands   case of invasive adrenal neoplasia.
            are located in variable positions close to the celiac and
                                   1
            cranial mesenteric arteries.  On CT images, the adrenal   Vascular disorders
            glands are soft‐tissue attenuating on unenhanced
            images and isoattenuating to liver on contrast‐enhanced   Adrenal masses can invade local vasculature, as
                                                               described above. In addition, they may rupture and
            images (Figure  5.6.1). The volume of the left adrenal
            gland is larger than the right in normal dogs. There is   cause intra‐abdominal or retroperitoneal hemorrhage.
                                                               The hemorrhage may be contained within the adrenal
            significant individual animal variation in size of the
            adrenal glands and no significant correlation with   gland capsule or free in the peritoneal or retroperitoneal
                                                               space. Hemorrhage appears as fluid‐attenuating, nonen-
            weight.  On MR images, the glands are T1 isointense to
                   2
            surrounding organs. On T2 images, the adrenal glands   hancing tissue within the retroperitoneal or peritoneal
                                                               cavity (Figure 5.6.5). Hemorrhage can occur in both vas-
            are isointense to the renal cortex and hyperintense to
            liver and musculature. The medulla is sometimes visible   cularly invasive and noninvasive masses and may be
                                                               life‐threatening.
                                                                            3
            as a hyperintense region compared to the cortex on fast
            spin-echo T1, T2, or T1 contrast‐enhanced images   Neoplasia
            (Figure  5.6.2).  Adrenal glands are intensely contrast
                         1
            enhancing on both CT and MR images.                Pituitary adenomas are responsible for pituitary‐
               The feline adrenal glands are more oval in shape com-  dependent hyperadrenocorticism (PDHAC), which is
            pared to those of the dog. They are similarly positioned   the most commonly diagnosed cause of Cushing’s syn-
            medial and lateral to the caudal vena cava and cranial to   drome in dogs and cats. Imaging features include bila-
            the left and right kidneys. In CT dual‐phase imaging of   terally and generally symmetrically enlarged adrenal
            both species, arterial enhancement is intense in the   glands without evidence of a mass (Figure 5.6.6, 5.6.7).
              cortex, and the gland is more uniformly enhancing in   In adrenal‐dependent hyperadrenocorticism (ADHAC),
            the venous phase (Figure 5.6.3). Feline adrenal glands   there is a primary adrenal mass (adenoma or carcinoma)
            are also visible on MR images, with imaging characteris-  that is responsible for the clinical signs (Figure 5.6.8).
            tics similar to those of the dog (Figure 5.6.4).   CT imaging can be used to evaluate both the brain and
               The common trunk of the caudal phrenic vein and   the adrenal glands to differentiate these two diseases.
            cranial abdominal vein (previously termed the phreni-  Pituitary macroadenomas are intensely contrast
            coabdominal vein)  passes lateral and ventral to  each   enhancing and are discussed further in Chapter  2.9.
            adrenal gland to drain into the caudal vena cava. The   However, pituitary glands affected by functional


            Atlas of Small Animal CT and MRI, First Edition. Erik R. Wisner and Allison L. Zwingenberger.
            © 2015 John Wiley & Sons, Inc. Published 2015 by John Wiley & Sons, Inc.
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