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108  Atlas of Small Animal CT and MRI

             Metastatic deposits tend to lodge in the lymphatic   always be detected on CT and MR images, and fine‐
             sinuses of affected nodes, and when macrometastases   needle  aspiration cytology is necessary for diagnosis.
             are present, filling defects can be identified on contrast‐  Lymphoma may also affect the lymph nodes of the
             enhanced images. On CT images, these need to be dis-  head and neck. Diffuse large‐cell B‐cell lymphoma
             tinguished from fat within the lymph node hilus, which   results in marked enlargement of the retropharyngeal
             can mimic a parenchymal filling defect. On MR images   and/or mandibular lymph node groups. The contrast
             of dogs with mast cell tumors, affected lymph nodes   enhancement in these lymph nodes is uniform with a
             were larger and more heterogeneous on T2 and contrast‐  slightly foamy appearance. Small lymph nodes that are
             enhanced images than normal lymph nodes.  Lymph    not normally identified, such as the parotid lymph node,
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             nodes in cats with metastatic disease from squamous cell   may become visible with increased size (Figure 1.8.10).
             carcinoma  were  not  significantly  larger  than  normal   T‐cell lymphoma may affect a single lymph node in the
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             lymph nodes.  Therefore, affected lymph nodes cannot   head with similar imaging characteristics.




              Figure 1.8.1  Normal Mandibular Lymph Nodes (Canine)                                         CT
                                                                              5y MC English Setter. Mandibular lymph node
                                                                              aggregates are seen ventrally (a: arrows).
                                                                              Normal mandibular nodes are variable in
                                                                              both size and number. Normal lymph nodes
                                                                              are highly and uniformly contrast enhancing
                                                                              (b). The facial vein (b: arrows) courses next to
                                                                              the lymph nodes and should be distinguished
                                                                              from them by viewing serial contiguous
                                                                              images (not shown).






             (a) CT, TP                       (b) CT+C, TP




              Figure 1.8.2  Normal Mandibular Lymph Nodes (Canine)                                        MR





















             (a) T1, TP                       (b) T2, TP                       (c) T1+C, TP
             1y M Shetland Sheepdog. Mandibular lymph node aggregates are seen ventrally, appearing isointense to muscle on T1 images (a: arrows)
             and hyperintense on T2 images (b: arrows). Normal mandibular lymph nodes are variable in both size and number. Normal lymph nodes
             are highly and uniformly contrast enhancing (c). The facial vein (b: arrowheads) courses next to the lymph nodes and can be  distinguished
             from the lymph nodes on MR by the flow void artifact.
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