Page 1032 - The Toxicology of Fishes

1012 The Toxicology of Fishes

buccal cavity, 65, 69 homeostasis, 469
Buffalo River, 710 influx, 463
bull trout (Salvelinus confluentus) intracellular, mercury and, 502
in Clark Fork River, 795, 796 ions, 441
TCDD sensitivity, 844 lead as mimic of, 441
bullhead (Ictalurus melas), 213; see also catfish loss of, from gills, 405
liver, GST–CDNB activity in, 198 metabolism, 296
buoyancy, 69 permeability, and, 405
1-butanol, 79 progesterone, and, 465
buthionine sulfoximine (BSO), 281, 304 sequestration, 435
butterfly fish, 166, 168 calcium-channel blockers, 361, 404
butylated hydroxyanisole (BHA), 198 calcium channels, 427, 435, 440, 441, 807
butyraldehyde, 179 Callinectes sapidus, 279
calmodulin, 440, 441, 463, 469
C inhibitors, 409, 468
C-18 steroids, 460 cAMP, 410, 461, 462, 463, 465, 466, 468, 469,
C-19 steroids, 460 476
C-21 steroids, 460, 461, 474 Campostoma anomalum, 623
14
[ C]-2,2′,5,5′-tetrachlorobiphenyl, 81, 117 Canadian Pulp and Paper Effluent Regulation, 934
14
14
[ C]-3,3′,4,4′-tetrachlorobiphenyl ([ C]-PCB 77), canalicular lumen, 337
18, 72 canaliculi
14
[ C]-benzo(a)pyrene, 18, 44 bile, 84, 85, 337, 338, 339, 343, 359, 692
2+
Ca , 403–404, 405, 407, 409, 441 liver, 63, 335, 337, 338, 363
2+
Ca -ATPase, 403, 407, 409 cancer, 4, 163, 164, 196, 208, 278, 295, 296, 307,
caddisfly (Hydropsyche sp.) 308, 498, 504, 509, 513, 532, 533, 534, 535,
copper concentrations in, 791, 792 536, 538, 539–549, 554–578, 599, 620; see
metal tolerance of, 793, 794 also carcinoma
cadherin, 441 as adaptive response, 607–608
cadmium, 11, 17, 80, 90, 91, 202, 205, 258, 286, BaP-induced, 539, 541, 542
300, 403, 404, 407–408, 409, 410, 411, 440, bladder, 538
469, 476, 477, 499–501, 603, 606, 662, 689, breast, 163, 164, 607
735, 781, 783, 784, 787, 789, 790, 792, 794, colorectal, 549
797, 799, 800 cottonseed kernels, and, 564
acclimation to, 611 crowding, and, 569
avoidance/attraction responses to, 442 DNA repair, and, 549
chloride cells, and, 404 environmental contaminants, and, 534–540
corticosteroid stress response, and, 475 liver, see liver cancer
genetic diversity, and, 623 methylation, and, 548
HSP30 induction, and, 691 modulators of, 566
HSP70, and, 691 oxidative stress, and, 307
metallotheoneins, and, 690 PAH-induced, 538, 603
permeability, and, 405 prevention, 567
pretreatment, 610 species differences in, 571
resistance to, 611 therapy, phase II enzymes and, 608
-resistant killifish, 622 viruses as cause of, 547–548
trophic transfer of, 736 Cap‘n’Collar basic leucine zipper (CnC-bZIP),
zinc, and, 500 258
caging studies, 952 Carassius auratus, 179, 433, 442, 497, 502, 561,
calcium, 13, 24, 29, 30, 31, 33, 81, 356, 357, 403, 987; see also goldfish
406, 435, 438, 444, 459, 462, 463, 468 carbamates, 185, 207, 213–215, 431, 432,
-binding protein (calmodulin), 463 433–434, 601, 807, 810
binding, disruption of by aluminum, 441 carbamylate esterase, 431
cadmium uptake, and, 407 carbaryl, 434