Page 1033 - The Toxicology of Fishes

Index 1013

carbocation, 200 bioassay of, 573–574
carbohydrates, 63 chemical, classes of, 537–539
carboligase, 206 dietary, 204
carbon, 285 DNA alterations, and, 542–549
aliphatic, 200 epigenetic, 548–549
black, 40, 43 metabolism of, 539–542
free radicals, 158 PAH-type, 208
hydroxylation, 157 carcinoma; see also cancer
organic, 12, 20, 39, 40, 41, 43, 128, 130, 882, epidermal, 710
883, 884 hepatocellular, 209, 537, 618, 619, 710
dissolved, 954 cholangiocellular, 367, 692
in sediment, 43, 129, 130 cardiac glands, 69
partition coefficients (K , K ), 40 cardiac output, 57, 68, 75, 79, 82, 86, 88, 96, 106,
poc
doc
partitioning, 12 111, 118, 119, 120, 405
TCDD, and, 40 cardiovascular toxicity, 829, 830, 842–843, 893
carbon dioxide, 14, 23, 428, 430, 439 β-carotene, 285
carbon disulfide, 427 carotenoids, 283, 285, 303
carbon monooxide, 154 carotinoids, 160
carbon tetrachloride (CCl ), 296, 350, 360, 368, carp, 182, 208, 252, 489
4
370–371, 563, 607 cadmium, and, 406
free-radical species, 370 Carassius auratus, APC homologs in, 561;
carbonate, 29, 30 see also goldfish
carbonyls, 190, 294 ceruloplasmin in, 286
carboxylesterase (CaE), 123, 182 c-myc in, 558
carboxylic acid, 66, 76, 185, 205, 424 Ctenopharyngodon idellus, WT-1 homolog
conjugation of, 205 in, 560
carcinogenesis, 5, 163, 197, 207, 512, 626, 822, Cyprinus carpio, 163
838, 890, 904, 908 3-methylcholanthrene, and, 511
AFB -induced, 211, 212, 213, 540, 552, 564, anterior kidney, 492
1
565, 566, 567 cadmium, and, 500
biomarkers for, 698 chromium, and, 501
β-naphthoflavone (BNF)-enhanced, 563 complement, 493
cellular adaptations during, 607 fenestrae, 341
chemical, 531–578 interleukin, 494
inhibition of, 566–567 lead, and, 443
resistant hepatocyte model of, 607 lindane, and, 507
crowding, and, 569 macrophages, 495
DEN-induced, 565, 567, 568 MDR inhibitors, and, 692
DMBA-induced, 553 mucosa, 492
environmental factors affecting, 568–570 pyrethroids, and, 505, 506
field studies, 574–577 sewage treatments works efluent, and,
hepatic, 209, 367, 375 974
host factors affecting, 570–573 surface immunoglobulin in, 490
immunlogic factors affecting, 567–568 thymus, 490
MNNG-initiated, 564 vitellogenic response in, 972
modifying factors in, 562–573 P-glycoprotein, and, 362
molecular biology of, 554–562 plasma, cadmium in, 80
multistage, 535–537, 548 viellogenin induction in, 974
carcinogenicity, 162, 203, 511 vitamin D receptor in, 356
carbon tetrachloride, 296 carrier-mediated transport, 63
quinone, 297 catalase, 279, 280, 286, 308, 373, 607, 694
carcinogens, 180, 190, 191, 207, 328, 531–578, inhibitors, 279
887 catechin, 204