Page 173 - Medicinal Chemistry Self Assessment
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162 Medicinal Chemistry Self Assessment
Chapter 2.13 (removed bolded drug names)
Answer
O O H NH 2
N N O
H 3 C O N N
N O(CH ) CH
N 2 5 3
CH 3
Dabigatran Prodrug
O O H NH 2
N N O
H O N N
2 5
N N O(CH ) CH 3
CH 3
O O H NH 2
N N
H 3 C O N NH
N
N
CH 3
O O H NH 2
N N
H O N NH
N N
CH 3
Active form of Dabigatran