Page 1024 - Small Animal Internal Medicine, 6th Edition
P. 1024

996    PART VIII   Reproductive System Disorders


              True priapism (ischemic or nonischemic) can be associ-
            ated with vascular disorders (efferent or afferent) or neu-
  VetBooks.ir  ropathy, or it can be idiopathic. A dysregulatory hypothesis
            for the pathophysiology of priapism has been postulated.
            Dysnergic neurostimulations of inflow and outflow penile
            blood  vessels  cause  prolonged  vascular  or  smooth  muscle
            spasms.  This  dysregulation  may  occur  at  the  level  of  the
            penis or at other regulatory levels of penile erection, includ-
            ing the central (spinal cord L1-4, S1-3) or peripheral nervous
            system (Lavely, 2009).
              Distinguishing ischemic (proceeds to gangrene) versus
            nonischemic priapism and identifying and treating the
            underlying cause is important. If determined to be ischemic,
            prompt aspiration of the corpora cavernosa under sedation
            or anesthesia with or without irrigation should be done.
            Intracavernosal injections of phenylephrine should be con-
            sidered. However, this may carry some risk as appropriate
            dosages in dogs and cats have not been determined. Starting
            with low dosages (1-3 mcg/kg) and cardiovascular monitor-
            ing, therefore, is important. Providing lubrication is impor-  FIG 56.16
            tant to limit tissue damage secondary to exposure and   Feline priapism in a tom cat overdosed with ace promazine.
            excoriation. An Elizabethan collar may be indicated. If intra-
            cavernosal drainage and injections are not successful or sig-
            nificant tissue damage has occurred, then penile amputation
            and perineal urethrostomy may become necessary.
              Nonischemic priapism can resolve spontaneously. Thus
            conservative therapy, protecting penile integrity with lubri-
            cation, and an Elizabethan collar are recommended. Several
            systemic medications are of potential benefit, although very
            little controlled data exists regarding efficacy of systemic
            drug therapy. Gabapentin, terbutaline, or pseudoephedrine
            should be tried. If detumescence is not achieved after several
            days of treatment with one drug, switching to another may
            be successful.
              Ischemic priapism has been reported in cats; penile
            amputation and perineal urethrostomy may be indicated. A
            traumatic cause should be considered in cats if they have a
            recent history of mating; it has also been reported after   FIG 56.17
                                                                 Ultrasound image of normal canine testes, sagittal view.
            orchiectomy. Surgical treatment making several small inci-
            sions bilaterally in the tunica albuginea of the corpora cav-
            ernosa penis and in some parts of the corpora cavernosa   clinical signs similar to phimosis, and is treated by clipping
            followed by irrigation with heparinized saline has been   the preputial hairs.
            reported to have some success. Skin sutures were then placed
            closing the approach, but the tunica albuginea was not   TESTICULAR NEOPLASIA IN STUD DOGS
            closed. Nonischemic feline priapism can respond to medical
            management as in the dog (Fig. 56.16).               Unless the dog is a valuable and still fertile stud, the discov-
              Phimosis is a condition in which the penis is trapped   ery of a testicular mass warrants castration. If the dog is still
            within the preputial cavity. It usually occurs as a congenital   breeding and the tumor is limited to one testis, unilateral
            defect in which the preputial opening is abnormally small   castration can be performed. Testicular neoplasia is rare in
            and the penis cannot protrude. Phimosis is uncommon in   the tom cat. Risk factors for testicular neoplasia in the dog
            cats and dogs. It may be recognized in young animals as a   are age (>10 years) and cryptorchidism. The early diagnosis
            cause of a urinary outflow tract obstruction or of the drib-  of testicular neoplasia is often incidental and based on careful
            bling of urine that has accumulated in the preputial cavity.   palpation of the scrotal testes. Ultrasound can detect testicu-
            Phimosis may be recognized in an affected postpubertal   lar masses too small for manual detection and is therefore
            male unable to copulate. It is treated by conservatively surgi-  indicated annually in valuable breeding dogs. The normal
            cally enlarging the preputial orifice. The preputial hairs of   testis is uniform in texture with echogenicity similar to the
            longhaired cats may entangle the preputial orifice, causing   spleen (Fig. 56.17). The mediastinum testis is a thin, centrally
   1019   1020   1021   1022   1023   1024   1025   1026   1027   1028   1029