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16  Imaging in Cardiovascular Disease  137

               Figure 16.10  Thoracic radiographs of a   (a)                           (b)
  VetBooks.ir  congestive heart failure secondary to
               Doberman with acute left‐sided
               dilated cardiomyopathy. Note the tracheal
               and carina dorsal elevation as well as the
               straightening of the caudal part of the
               cardiac silhouette, suggesting left heart
               enlargement on the lateral view (a). Diffuse
               patchy interstitial and alveolar opacities
               consistent with cardiogenic pulmonary
               edema are also present. They are
               symmetrically distributed in the right and
               left lung fields on the dorsoventral view
               (b). Source: Medical Imaging Unit, ENVA.










               atrial septal defects (Figure  16.16b) and mitral valve   septal thickness at end‐diastole and at end‐systole
               lesions (Figure 16.16c).                           (which correspond to the onset of qRs and end of T‐
                 The right parasternal long‐axis five‐chamber view is   wave,  respectively, on  concomitant ECG tracing), in
               commonly used to examine the left ventricular outflow   order to detect and quantify left ventricular alterations
               tract, the mitral valve leaflets, and the junction between   (Figure  16.20a and 16.20b). The left ventricular frac-
               the interventricular septum and the anterior aortic wall   tional  shortening  can  then  be  calculated  to  indirectly
               in order to respectively diagnose left ventricular out-  assess the transverse systolic myocardial function
               flow tract obstruction (Figure  16.17b), mitral valve   (Figure 16.19a; see also Tables 16.4 and 16.5). The M‐
               lesions (Figure  16.17c), and ventricular septal defects   mode echocardiogram obtained at the ventricular level
               (Figure 16.17d).                                   can also be used to measure right  ventricular dimen-
                 Long‐axis four‐ and five‐chamber views can also be   sions (end‐diastolic diameter and end‐systolic myocar-
               obtained from the left parasternal position (2D left apical   dial wall thickness).
               or caudal four‐ and five‐chamber views; Figure 16.18).  E point to septal separation (up to 5–8 mm in the dog,
                 The left apical four‐chamber view provides good visu-  depending on the size of the animal) can be measured
               alization of the ventricular inflow tracts and is therefore   from M‐mode echocardiograms obtained at the mitral
               used to assess mitral and tricuspid diastolic inflows. It   valve level. This distance increases in the case of severely
               may also be used to calculate end‐diastolic and end‐sys-  reduced systolic left ventricular function. The same M‐
               tolic left ventricular volumes (Box 16.1).         mode view may be used to detect systolic anterior motion
                 The end‐diastolic left ventricular length can also be   of the mitral valve, which is commonly associated with
               measured from the left apical four‐chamber view and the   obstructive forms of feline hypertrophic cardiomyopathy
               index of sphericity can then be calculated (this index is   (Figure 16.20c).
               defined as the end‐diastolic left ventricular length / left
               ventricular diameter assessed by M‐mode at end‐dias-
               tole; normal values are usually >1.65). The main use of the
               left apical five‐chamber view is for the Doppler assess-    Conventional Doppler
               ment of systolic aortic outflow.                   Echocardiography

                                                                  Conventional Doppler echocardiography allows detection
               Standard M‐Mode Views and Measurements
                                                                  and  analysis  of  blood  flows  within  the  cardiovas cular
               The two most commonly used M‐mode echocardio-      system. The conventional Doppler examination consists
               grams are obtained at the ventricular level and the mitral   of locating blood flows within the cardiac chambers and
               valve level (Figure 16.19). The M‐mode echocardiogram   vessels, as well as assessing their direction, velocity, and
               obtained at the ventricular level is used to measure left   duration.  This  technique  is  also  used  to  differentiate
               ventricular end‐diastolic and end‐systolic diameters,   normal laminar flows from abnormal nonlaminar (or
               left ventricular free wall thickness and interventricular   turbulent) flows. Additionally, flow  volumes and pressure
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