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138  Section 3  Cardiovascular Disease

                (a)                                           mation, and has now supplanted invasive techniques
  VetBooks.ir                                                 such as cardiac catheterization for the diagnosis of most
                                                              human and animal heart diseases. Advanced ultrasound
                                                              imaging techniques beyond the scope of this chapter are
                                                              summarized in Box 16.2.


                                                              Basic Principles

                                                              Conventional Doppler echocardiography is based on
                                                              the Doppler principle, discovered by Christian Doppler
                                                              in the 19th century, which states that a moving struc-
                                                              ture (e.g., blood cells) reflects the incident ultrasound
            (b)                                               beam back to the transducer with a higher or lower
                                                                frequency than the original transmitted frequency
                                              (c)             depending on whether the structure is, respectively,
                                                              moving toward or away from the transducer. This dif-
                                                              ference between transmitted and received frequencies,
                                                              also called the Doppler shift or frequency shift, is
                                                              directly related to the velocity of the reflecting moving
                                                              structures, which can thus be deduced from the fre-
                                                     Rib 9    quency shift analysis.
                                                                The recorded frequency shift (and therefore the calcu-
                                                              lated flow velocity) also depends on the cosine of the inter-
                                                              cept angle (θ) between the ultrasound beam and blood
                                                              flow path. Therefore, whichever Doppler mode is used,
                                      Rib 9
                                                              the incident ultrasound beam must be perfectly parallel to
                                                              the  blood  flow  path  (θ  = 0°), otherwise the blood  flow
                                                              velocity will not be assessed correctly, that is, it will be
            Figure 16.11  Thoracic radiographs of two dogs with marked   underestimated as compared to the actual velocity.
            right heart enlargement resulting from severe pulmonic stenosis
            (a) and pulmonary arterial hypertension secondary to a large   As frequency shift values are usually within the hear-
            reversed ventricular septal defect (b,c). (a) Note on this lateral   ing range of the human ear, an audible signal can be
            view the increased sternal contact of the cranial cardiac margin   simultaneously associated with spectral Doppler trac-
            (small arrows) consistent with right ventricular enlargement, as   ings of flow velocities. Listening to this Doppler audio
            well as protrusion of the dorsal cranial margin of the cardiac   signal is particularly useful in practice to help in align-
            silhouette (large arrow) owing to both right atrial dilation and
            enlargement of the main pulmonary artery. The pulmonary   ing the ultrasound beam parallel to blood flow: the
            vasculature is also slightly diminished. (b) On this dorsoventral   louder the audible signal, the higher the Doppler shift,
            view, right ventricular enlargement is characterized by a rounded   the smaller the intercept angle θ, the better the align-
            right heart border bulging to the right (approximately between 6   ment between blood flow and the ultrasound beam.
            and 9 o’clock; arrows) and a leftward shift of the cardiac apex,
            leading to a reverse‐D appearance. Note also the marked
            prominence of the main pulmonary artery (MPA) between 1 and   Standard Doppler Modes
            2 o’clock and the enlarged peripheral pulmonary arteries (PA),
            compared with the pulmonary veins (V, see details on (c)), which   Standard Doppler echocardiography includes differ-
            indicates pulmonary arterial hypertension. Width of peripheral   ent  complementary  modes,  spectral  Doppler  modes
            pulmonary arteries should be similar to that of the corresponding
            pulmonary veins and should not be larger than the ninth rib   and color‐flow Doppler mode (see examples on
            diameter at the crossing point between the two. Source: Medical   Figures 16.21–16.23). Each mode has specific advan-
            Imaging Unit, ENVA.                               tages and limitations, of which the observer must be
                                                              perfectly aware in order to avoid misinterpretation of
                                                              the recorded Doppler signals.
            gradients across valves or between cardiac chambers can
            be estimated from velocity Doppler data using specific   Spectral Modes: Pulsed‐Wave and Continuous‐
            equations.  Conventional  Doppler  echocardiography   Wave Doppler Modes
            complements 2D and M‐mode echocardiography by     The two main spectral Doppler modes are pulsed‐wave
            providing accurate cardiovascular hemodynamic infor-  (PW) and continuous‐wave (CW) Doppler modes.
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