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128 / Chapter 9 White cells: Lymphocytes
PRIMARY LYMPHOID ORGANS
Bone marrow
B > T
CD8 > CD4
Thymus
+
Cortex TdT
-
Medulla TdT
SECONDARY LYMPHOID ORGANS
Lymph node
Mantle zone
Deep Follicle
cortical area Cortex
(paracortex)
Medullary
cords
Spleen
T-cell (marginal) area
Germinal centre
Mantle zone
Red pulp
Blood
T > B
CD4 > CD8
Figure 9.2 Primary and
B-cell areas T-cell areas secondary lymphoid organs
and blood. TdT, terminal
deoxynucleotidyl.