Page 273 - Essential Haematology

Chapter 20 Non-Hodgkin lymphoma / 259

ypical cytogenetics 13q14, 17p or 11q deletions; trisomy 12 No specific findings t(1; 14) t(14; 18) t(11; 14) t(3; 14) t(14; 18) t(8; 14) t(2; 8) t(8; 22)

Cyclin D T 1 − − − + − −

BCL 6 - − − − + − − / + +

Characteristic immunophenotype and cytogenetics of B cell lymphomas.
BCL 2 - + + + + + − / + −

CD23 + − − / − / − − −

- + +
CD20 + + + + + + +

CD10 − − − + − − / + +

CD5 + − − − + − −

Surface immunoglobulin Weak − / + + + + − / + + CLL, chronic lymphocytic leukaemia; MALT, mucosa - associated lymphoid tissue. More detailed cytogenetics are given in Table 11.1 .

Lymphoplasmacytic Follicular lymphoma
able 20.3 T Lymphoma CLL/lymphocytic lymphoma MALT lymphoma Mantle cell lymphoma Diffuse large cell lymphoma Burkitt lymphoma