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CHAPTER 5
Megaloblastic
a naemias and
o ther m acrocytic
a naemias
Key topics
■ Megaloblastic anaemias 59
■ Vitamin B 12 59
■ Folate 62
■ Vitamin B 12 defi ciency 63
■ Folate defi ciency 64
■ Clinical features of megaloblastic anaemia 65
■ Diagnosis of vitamin B 12 or folate defi ciency 67
■ Other megaloblastic anaemias 71
■ Systemic diseases associated with folate or
vitamin B 12 defi ciency 71
■ Other macrocytic anaemias 71
Essential Haematology, 6th Edition. © A. V. Hoffbrand and P. A. H. Moss. Published 2011 by Blackwell
Publishing Ltd.