Page 13 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

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VetBooks.ir Puberty 281 19. Ionizing Radiation in Veterinary
Normal Male Reproductive Anatomy
Medicine
281
and Physiology
Normal Female Reproductive Anatomy Lisa Murphy
and Physiology 286
Introduction to Ionizing Radiation 327
Oocyte/Sperm Transport, Normal
Alpha and Beta Particles 327
Capacitation of Sperm and Fertilization 290
Gamma Rays and X-rays 327
The Endocrinology of Pregnancy and
Measuring Ionizing Radiation 328
Placentation 291
Sources of Radiation 328
Normal Embryonic and Fetal Development 292 Natural Sources 328
Parturition and Lactation 295 Nuclear Weapons 328
The Mechanisms and Effects of Reproductive Nuclear Power 328
Toxicants 296 Sterilization of Food 329
The Effects of EDCs on Wildlife Species, Medical Uses of Radiation in Human and
Humans and Domestic Animals 296 Veterinary Medicine 329
Toxicants Affecting the Male Reproductive Absorption, Distribution, and Accumulation
Function 299 of Radioactive Contaminants in Animals 329
Toxicants Affecting the Female Acute Effects of Radiation Exposure in
Reproductive Function 303
Animals 330
Teratogenesis and Abortion 305
Long-Term Impacts of Radiation Exposure in
Concluding Remarks 312
Animals 332
References 313
Mitigating Acute Radiation Exposures in
Further Reading 316
Animals 333
Minimizing Exposure 333
Prophylaxis 333
Section III Triage and Screening 334
Decontamination 334
Nanoparticles, Radiation and Additional Treatments and Monitoring 334
Carcinogens Concluding Remarks and Future Directions 335
References 335
18. Toxicity of Nanomaterials
20. Carcinogenesis: Mechanisms and
Deon van der Merwe and John A. Pickrell
Models
Introduction 319
Supratim Choudhuri, Ronald Chanderbhan
Nanomaterials Characterization 321
and Antonia Mattia
Animal or Tissue Exposures 321
In Vitro Exposures to Nanomaterials 321 Introduction 339
Intratracheal Instillation Pharyngeal Terminology 339
Aspiration 322 Agents Causing Carcinogenesis 339
Ultrafine Particles 322 Chemical Carcinogenesis 339
Carbon Nanotubes 322 Oncogenes, Tumor Suppressor Genes,
Intranasal Exposure 323 and the Genetic Basis of Carcinogenesis 348
Inhalation Exposure 323 Radiation Carcinogenesis 350
Epidemiological Data 323 Epigenetic Basis of Carcinogenesis 351
Sulfur Dioxide (Oxides of Sulfur Epigenetic Changes During Carcinogenesis
Particles) 323 Have Been Widely Studied and Well
Swine Barn Dust Exposure 323 Documented 351
Nanoparticle Exposure in the Home 324 Classification of Carcinogens 352
Dog Exposures to Automobile Exhaust Assays for Carcinogens 352
Aerosols 324 Concluding Remarks and Future
Emerging Challenges 324 Directions 353
References 325 References 354