Page 15 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

xiv Contents

VetBooks.ir Pharmacokinetics and Mechanism of Action 429 Background 455
430
Toxicity
Toxicokinetics
456
431
Treatment
Mechanism of Action
457
Concluding Remarks and Future Directions 431 Toxicity 458
References 431 Nervous System 458
Renal System 459
28. Iron Cardiovascular System 459
GI Tract 459
Stephen B. Hooser
Hematopoietic System 460
Introduction 433 Other Effects 460
Background 433 Diagnosis 460
Pharmacokinetics/Toxicokinetics 433 Treatment 460
Mechanism of Action 434 Concluding Remarks and Future Directions 460
Toxicity 434 References 460
General 434
Acute Toxicity in Dogs, Cattle, Pigs 32. Molybdenum
and Adult Horses 435
Neonatal Pigs 435 Jeffery O. Hall
Neonatal Horses 435 Introduction 463
Iron Storage Disease 436 Background 463
Treatment 436 Pharmacokinetics/Toxicokinetics 463
Concluding Remarks and Future Directions 436 Absorption 463
References 436 Distribution 464
Elimination 464
29. Lead Mechanism of Action 464

Larry J. Thompson Toxicity 465
Treatment 465
Introduction 439 Concluding Remarks and Future Directions 466
Background 439 References 466
Toxicokinetics 439
Mechanism of Action 440 33. Selenium
Toxicity 440
Treatment 441 Jeffery O. Hall
Concluding Remarks and Future Directions 442 Introduction 469
References 442 Background 469
Pharmacokinetics/Toxicokinetics 470
30. Manganese Absorption 470
Distribution 471
Dejan Milatovic and Ramesh C. Gupta
Metabolism 471
Introduction and Background 445 Elimination 471
Pharmacokinetics/Toxicokinetics 446 Mechanism of Action 472
Mechanism of Action 447 Toxicity 472
Toxicity 449 Treatment 474
Diagnosis 450 Concluding Remarks and Future Directions 474
Treatment 450 References 474
Concluding Remarks and Future Directions 451
Acknowledgments 451 34. Sodium Chloride (Salt)
References 451
Larry J. Thompson
31. Mercury Introduction 479
Background 479
Ramesh C. Gupta, Dejan Milatovic, Rajiv Lall
Pharmacokinetics and Mechanism of Action 480
and Ajay Srivastava
Toxicity 480
Introduction 455 Treatment 481