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772 APPROCHES THÉRA PEUTIQUES DIVERSES
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• Utilisations
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- Prodrogues
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drugs that release a primary amine via nitroreduction and intramolecular cyclisation,
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- GD-tex
YOUNG S.W. et al., gadolinium(lll) texaphyrin : a tumor selective radiation sensitizer that
is detectable by MRI, Proc. Nat/. Acad. Sei. USA, 1996, 93, 6610-6615.
ROSENTHAL D.I. et al., A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a
tumor selective radiation sensitizer detectable by magnetic resonance imaging, Clin.
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BERNHARD E.J. et al., Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing
agent, Cancer Res., 2000, 60, 86-91.