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            Disease Complication in a Geriatric Pig-Tailed Macaque (Macaca nemestrina) from Wildlife
                                            Rescue Centre (WRC) Jogja
                       Irhamna Putri Rahmawati , Novra A. Sandi , Andreas Bandang Hardian
                                               1
                                                                                          4,*
                                                               2,3
              1 Wildlife Rescue Centre (WRC) Jogja, Yayasan Konservasi Alam Yogyakarta (YKAY) Jl. Pengasih-
              Nanggulan, Paingan, Sendangsari, Pengasih, Kulonprogo, Special Region of Yogyakarta 55652
            2 Eijkman-Oxford Clinical Research Unit (EOCRU), Eijkman Institute for Molecular Biology (EIMB), Jl.
                                     Pangeran Diponegoro No.69, Jakarta 10430
            3 Department of Paraclinical Science, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan,
                           1275, Jalan Padang Tembak, Pengkalan Chepa, Kelantan 16100
                4 Laboratory of Veterinary Anatomic Pathology, Faculty of Veterinary Medicine, Universitas
                 Brawijaya, Jl. Puncak Dieng, Kunci, Kalisongo, Dau, Malang, East Java, Indonesia 65151

                                    *Correspondence: andreasbandangh@ub.ac.id

                                                      ABSTRACT

           A geriatric male pig-tailed macaque was found having a mass growing up in the left shoulder for more than five
           months.  It  was  an  approximately  4x4x2  cm,  firm,  hairless  focal  non-encapsulated  mass  suspected  as  skin-
           derivative tumour. We performed a cytological test on the mass and skin biopsy to see the tissue content of the
           mass. Histopathologic finding confirmed that the mass was identic to papilloma. The mass was then extracted.
           However, the health condition of the macaque was gradually deteriorated after surgery. Haematological tests
           were  done  three  times  during  post-surgery  period,  and  the  values  showed  gradually  increased  of  leukocyte
           number, indicating a developing chronic inflammatory response. The erythrocyte level was in normal range though
           the declining trend was observed suspecting to a progressing anaemia. A month after, the macaque suffered
           from general muscle stiffness, a clinical sign of tetanus. The ATT serum was given once though the macaque was
           found dead eventually.  Necropsy finding confirmed a significant chronic bilateral diffusive pneumonia. This case
           showed unpredicted sequence of disease occurrence in geriatric macaque after undergone the initial surgery of
           cutaneous  mass  extraction.  Hence,  the  routine  regular  health  screening  coupled  with  clinical  laboratory
           examination may assist the early detection based on the subclinical signs of disease in geriatric animals in
           rehabilitation centres.

           Keywords: conservation, disease, geriatric, pig-tailed macaque, rehabilitation






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