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                 (c)




























               Figure 31.17  A 15-year-old DSH presented for mass over the right caudal abdomen and right rear limb. A large complex mass
               involving the right caudal abdomen and pelvic region is noted on both the lateral (a) and ventrodorsal (b) images of the pelvic region.
               There is faint contrast enhancement of the outer rim of this large pedunculated mass found on a postcontrast transverse CT image (c).
               The extent of the mass was determined from the CT exam; the mass begins cranial to the level of the fourth lumbar vertebrae and
               caudally involving the rear limb. The mass extends immediately adjacent to the vertebral body and right ilial body and wing.
               Enlargement of the medial iliac lymph nodes is noted. This mass was diagnosed as a sarcoma.


               A chronic inflammatory response is induced by the injected   evaluation is necessary. Local invasion is more common than
               material, resulting in progression to neoplasia. These tumors   distant metastasis. The lungs, lymph nodes, and abdominal
               are more aggressive compared to noninjection site sarcomas.   organs are the most common metastatic sites. Local excision
               The incidence in vaccination sites has been reported to be   with radiation therapy improves survival but local recurrence
               1.3/1000 to 1/10 000 [15]. The age at presentation has two   still occurs in 28–45% of cases [14].
               distinct peaks, 6–7 years and 10–11 years. The inflammatory   Imaging of the tumor with survey radiographic images
               response makes cytologic diagnosis unreliable, so histopathologic   may  show  a  soft  tissue  mass.  Bone  lysis  can  be  difficult
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