Page 2814 - Cote clinical veterinary advisor dogs and cats 4th

Ephedrine Estriol (Incurin) 1477

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Ephedrine Anesthesia-related Anesthesia-related Can cause CNS stimulation, Injection (tablets no longer
available). Dilute dose into
tachycardia, hypertension, or
hypotension: 0.15-
hypotension: 0.15-
0.25 mg/kg diluted into
anorexia. Use with extreme
0.25 mg/kg diluted into
5 mL of saline or other
5 mL of a balanced
electrolyte solution or 5 mL of a balanced caution if at all in nursing electrolyte solution, and
animals. Contraindicated in
give in small IV boluses.
electrolyte solution
saline, and give small- or saline, and give severe cardiovascular disease
increment IV boluses to small-increment IV boluses and arrhythmias. Use with
effect to effect caution in glaucoma, prostatic
hypertrophy, hyperthyroidism,
DM, cardiovascular disorders, or
hypertension.
Epinephrine (Adrenalin) Anaphylaxis: 1-5 mL Anaphylaxis: 20 mcg/kg IV Can cause anxiety, tremor, Injection; confirm
(1 : 10,000 solution CPR: 0.01 mg/kg IV q 3-5 excitability, vomiting, hypertension, concentration before use.
= 0.1 mg/mL) SQ, or minutes early in CPR; up arrhythmias. Contraindicated in New labeling standards in
0.01 mg/kg IM to 0.1 mg/kg IV may be shock due to nonanaphylactoid some locations now avoid
CPR: 0.01 mg/kg IV q 3-5 considered after prolonged causes, during general anesthesia ratio expressions used
minutes early in CPR; CPR with halogenated hydrocarbons, formerly; what was called
0.1 mg/kg IV may be DCM or coronary insufficiency; 1 : 1000 epinephrine is now
considered after cases in which vasopressor labeled as 1 mg/mL, while
prolonged CPR. drugs are contraindicated 1 : 10,000 epinephrine is
Intratracheal alternative (e.g., thyrotoxicosis, hypertension). 0.1 mg/mL.
0.03-0.1 mg/kg Use extreme caution in patients
with a prefibrillatory cardiac
rhythm.
Ergocalciferol (Calciferol, Hypocalcemic tetany: Hypocalcemic tetany: Can cause hypercalcemia. Calcitriol Tablets, capsules
Drisdol) 4000-6000 units/kg PO 4000-6000 units/kg PO is safer and generally preferred
q 24h initially and then q 24h initially and then over ergocalciferol; however,
1000-2000 units/kg PO q 1000-2000 units/kg PO q ergocalciferol may be less
24h to once weekly 24h to once weekly expensive.
Erythromycin Promotility agent: 0.5-1 mg/ Promotility agent: 0.5-1 mg/ GI upset or pain is the most common Injection, tablets, topical.
kg PO q 8h kg PO q 8h adverse effect. Allergic reactions Currently injection and
Susceptible infections: Susceptible infections: are rare. Painful on IM injection. tablets are difficult to
10-20 mg/kg PO q 8-12h 10-20 mg/kg PO q 8-12h Multiple drug interactions. obtain for veterinary use.
Although formerly cost
effective, it has become
expensive.
Erythropoietin (EPO, Erythropoiesis: 100 units/ Erythropoiesis: 100 units/kg Adverse effects include autoantibody Injection. Iron
rHuEPO, Epogen, Procrit) kg SQ 3×/wk until the SQ 3×/wk until the low end development, causing worsened supplementation suggested.
low end of the target of the target hematocrit anemia, vomiting, hypertension,
hematocrit range is range is achieved, then seizures, uveitis, iron depletion,
achieved, then once once weekly. local reactions at injection
weekly. sites, fever, arthralgia, and
mucocutaneous ulcers.
Contraindicated in uncontrolled
hypertension.
Esmolol (Brevibloc) Short-term control of SVT: Short-term control of SVT: Can cause hypotension or Injection vials or premixed
0.05-0.1 mg/kg/min IV 0.05-0.1 mg/kg/min IV CRI, bradycardia. Contraindicated in ready-to-administer bags.
CRI, titrated to effect. titrated to effect overt cardiac failure, 2nd- or Injection diluted in saline or
Can administer 3rd-degree AV block, bradycardia, D 5 W before administration.
intermittent IV bolus of or in cardiogenic shock. Use with
0.05-0.1 mg/kg q 5 caution in CHF, bronchoconstrictive
minutes up to a maximum lung disease, or DM.
of 0.5 mg/kg
Esomeprazole (Nexium) Proton pump inhibitor Use is not described for cats. Seldom used in dogs. Use caution in Tablets OTC
antacid: 1 mg/kg PO q patients with hepatopathy. Multiple
24h drug interactions.
Estriol (Incurin) Hormone-responsive urinary Dosing in cats is not Adverse effects are GI- and Tablets
incontinence: 2 mg PO described. estrogen-related; bone marrow
q 24h for 14 days then depression risk appears to be low
taper to lowest effective with this estrogen.
dose
Drug Compendium

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