Page 2815 - Cote clinical veterinary advisor dogs and cats 4th

1478 Ethanol Fenbendazole (Panacur, Safe-Guard)

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Ethanol Ethylene glycol poisoning— Ethylene glycol poisoning— Fomepizole is preferred for both Use either Everclear (190
species (higher dose for cats),
CRI or intermittent-dose
CRI or intermittent-dose
proof, equals 95% ethanol)
strategy:
or plain vodka (80 proof,
strategy:
but availability and expense may
CRI: loading dose of 8.6 mL/
kg slow IV of 7% alcohol CRI: loading dose of 8.6 mL/ prevent use. Adverse effects of equals 40% ethanol). To
ethanol include CNS and respiratory
kg slow IV of 7% alcohol
make ethanol solution,
solution, followed by solution, followed by depression, hypoglycemia, diuresis, divide desired final %
1.43-2.86 mL/kg/h CRI 1.43-2.86 mL/kg/h CRI for as well as pain and infection at the solution by ethanol % in
for 48 hours 48 hours injection site. Avoid extravasation. product and multiply by
Intermittent-dose strategy: Intermittent-dose strategy: Monitor fluid, electrolyte, and mL of fluid in bag (e.g.,
5.5 mL/kg of a 20% 5.5 mL/kg of a 20% respiratory status; monitor blood 5% dextrose) to give the
solution IV over 1 hour q solution IV over 1 hour q alcohol levels. volume of fluid to be
4h for 5 treatments, then 4h for 5 treatments, then replaced by ethanol. For
q 6h for four additional q 6h for four additional example, to make 7%
treatments, each dose treatments, each dose ethanol using Everclear,
being given over 1 hour being given over 1 hour (7%/95%) × 1000 mL D 5 W
- 74 mL, meaning remove
74 mL of fluid from liter
bag and add 74 mL of
Everclear. To make 20%
solution using 80 proof
(40% ethanol) vodka in
a 1-liter bag of D 5W,
(20%/40%) × 1000 mL =
500 mL, remove 500 mL
of fluid from bag and
replace with 500 mL of
vodka.
Etidronate (Didronel) Hypercalcemia of Hypercalcemia of malignancy: Adverse effects include esophagitis, Tablets; give on empty
malignancy: 5-30 mg/ 5-20 mg/kg PO q 24h or GI upset, renal damage, and bone stomach.
kg PO q 24h or divided divided q 12h pain. Contraindicated in renal
q 12h impairment, delayed esophageal
emptying, upper GI inflammation or
ulcers, and bone fractures.

F

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
Famciclovir (Famvir) Dosing in dogs is not described. Feline herpesvirus type 1 Generally well tolerated, but anorexia and Tablets
(FHV-1): 90 mg/kg PO q polydipsia have been noted in some
12h, or 125 mg/CAT PO q 8h cats.
Famotidine (Pepcid) H 2 antagonist antacid: H 2 antagonist antacid: Well tolerated, but use with caution Tablets, chewable
0.5-1.1 mg/kg PO, IM, SQ, or 0.5-1.1 mg/kg PO, IM, SQ, in severe cardiac, hepatic, or renal tablets, disintegrating
IV q 12-24h or IV q 12-24h dysfunction (consider dose reduction). tablets, coated tablets,
Rapid IV administration might cause oral suspension, and
bradycardia or hemolysis (cats). injection. Oral forms
OTC.
Felbamate (Felbatol) Adjunctive antiepileptic: Dosing in cats is not Generally well tolerated. Use is typically Tablets, oral suspension
15-20 mg/kg PO q 8h, up to described. after multiple other agents have failed.
70-80 mg/kg PO q 8h
Fenbendazole (Panacur, Susceptible helminth infections: Susceptible helminth Adverse effects include GI upset; bone Oral granules, oral
Safe-Guard) 50 mg/kg PO q 24h; duration infections: 50 mg/kg PO marrow suppression rarely reported. suspension. OTC
usually longer for respiratory (7 q 24h (not FDA approved formulations.
days) than GI (3 days) parasites in cats)
Prophylaxis in pregnant bitch:
25 mg/kg PO q 24h from 40
days of pregnancy until 2 days
after whelping

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