Page 2818 - Cote clinical veterinary advisor dogs and cats 4th

Gabapentin (Neurontin) GoLYTELY (polyethylene glycol-electrolyte solution) 1481

G

VetBooks.ir Generic Name (Brand Canine Dosages Feline Dosages Adverse Effects/Warnings Administration/
Availability
Name, Synonyms)
Gabapentin (Neurontin) Adjunctive analgesia: 10-20 mg/ Adjunctive analgesia: 5-10 mg/ Human liquid dosage forms may Tablets, capsules, and oral
kg PO q 8-12h kg PO q 8-12h contain xylitol; do not use these in solution. Compounding
Adjunctive therapy for refractory Adjunctive anticonvulsant: dogs. Sedation and ataxia are the pharmacies may prepare
epilepsy: 10-30 mg/kg PO q 5-20 mg/kg PO q 6-12h most common adverse effects. xylitol-free oral liquids.
6-8h Reduce fear responses and
anxiety associated with
veterinary examinations:
50-100 mg/CAT PO once
before visit
Gemcitabine (Gemzar) Antineoplastic: 45 mg/ Antineoplastic: 25 mg/m Adverse effects are primarily GI toxicity Injection; cytotoxic, NIOSH-
2
m -900 mg/m , usually given diluted and given IV slowly and myelosuppression. listed hazardous drug
2
2
IV over 30-60 minutes q twice weekly (consult and should be prepared,
7-14 days (consult veterinary veterinary oncologist before administered, and
oncologist before use) use) disposed of in accordance
with federal and local
requirements.
Gemfibrozil (Lopid) Hyperlipidemia: 150-300 mg/DOG Hyperlipidemia: 7.5-10 mg/kg Generally well tolerated but abdominal Tablets; give 30 minutes
or 10 mg/kg PO q 12h PO q 12h (anecdotal) pain, GI upset, and abnormal liver before a meal.
function tests have been reported.
Gentamicin (Gentocin, Susceptible infections: 9-14 mg/ Susceptible infections: 5-8 mg/ Nephrotoxicity, ototoxicity, and Injection, ophthalmic and otic
Garamycin) kg IV, IM, or SQ q 24h kg IV, IM, or SQ q 24h neuromuscular blockade. Cats may preparations, and topical
Sighthounds: 6 mg/kg IV q 24h Otitis: Apply q 8h be more sensitive to toxic effects, creams
or 9 mg/kg SQ, IM q 24h Susceptible ocular infections: especially vestibular effects. Risk of
Otitis: apply q 8h Apply q 8h nephrotoxicity increased in animals
Susceptible ocular infections: Chemical enucleation: 25 mg with dehydration, pre-existing
apply q 8h injected into vitreous renal disease, extremes of age,
Chemical enucleation: 25 mg hypokalemia, and with treatment
injected into vitreous duration. Some ophthalmic
preparations contain steroids
and should not be used in fungal
keratitis.
Glipizide (Glucotrol) Do not use in dogs. Diabetes mellitus: Adverse effects include GI upset, Tablets; give with meals.
2.5-5 mg/CAT PO q 12h hypoglycemia, and liver toxicity.
with food May take 4-8 weeks to achieve
full effect, and loss of efficacy
is common. Contraindicated in
ketoacidosis or with severe illness.
Use with caution in cats with
concurrent endocrinopathy.
Glucosamine-chondroitin Adjunctive therapy of Adjunctive therapy of Effects may take 4-6 weeks. Dietary Tablets, capsules, and
sulfate (Cosequin) osteoarthritis: 15-30 mg/kg osteoarthritis and lower supplements are not regulated by powders; give with food.
(of the chondroitin component) urinary disease: 15-30 mg/ the FDA and are of varying quality.
PO q 24h then taper to lowest kg (of the chondroitin Do not switch brands. Ingredients
effective dose component) PO q 24h then are from natural sources (e.g., blue
taper to lowest effective dose crab, exoskeletons, cartilage), and
hypersensitivity is possible. Some
products contain high levels of
potassium. GI upset is mild and
self-limiting.
Glycopyrrolate (Robinul) Treatment of muscarinic signs Treatment of muscarinic Rarely used in small animals; Injection, tablets
of organophosphate poisoning: signs of organophosphate may be useful as an adjunct
0.01-0.02 mg/kg SQ, IM, IV poisoning: 0.01-0.02 mg/kg in treating muscarinic signs of
prn q 8-12h SQ, IM, IV prn q 8-12h organophosphate or carbamate
toxicity. Adverse effects include
tachycardia, arrhythmias, intestinal
ileus, mydriasis, and photophobia.
Glycosaminoglycan- Degenerative joint disease: Chondroprotective: 2 mg/ Occasional pain at injection site. May Injection
polysulfated (Adequan, 4.4 mg/kg IM twice weekly for kg IM q 3-5 days for 4-6 disrupt hemostasis in dogs.
Chondroprotec) up to 4 weeks treatments
GoLYTELY (polyethylene Large bowel cathartic: 22-33 mL/ Large bowel cathartic: Withhold food; pretreatment with Powder for solution
glycol-electrolyte solution) kg PO or via stomach tube 20-30 mL/kg via stomach antiemetic should be considered.
twice, 2 hours apart, 12 hours tube twice, 2 hours apart, 12 Aspiration can be fatal.
before GI endoscopy. Some hours before GI endoscopy Drug Compendium
dogs will drink willingly if mixed
with broth.

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