Page 2816 - Cote clinical veterinary advisor dogs and cats 4th

Fentanyl (Sublimaze, Duragesic) Flumazenil (Romazicon) 1479

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Fentanyl (Sublimaze, Analgesia: Injection—0.01- Analgesia: Injection—0.01- Use with caution in geriatric, ill, or Injection, transdermal
0.04 mg/kg SQ, IM, IV;
debilitated patients and in those with
Duragesic)
patches. CSS-II.
0.04 mg/kg SQ, IM, IV;
CRI—0.003-0.006 mg/kg/h
CRI—0.003-0.006 mg/
a pre-existing respiratory problem
(3-6 mcg/kg/h) IV; Patches—
5-10 kg = 25 mcg/h; kg/h (3-6 mcg/kg/h) IV; or CNS depression. Adverse effects
include dose-related respiratory,
Patches—2.5-mg patch
10-20 kg = 50 mcg/h; (= 25 mcg/h) CNS, and circulatory depression
20-30 kg = 75 mcg/h; >30 kg (bradycardia); also urine retention,
= 100 mcg/h constipation, dysphoria, or agitation.
Naloxone can reverse mu but not
kappa-receptor effects. Dogs may
become dysphoric when used as
a postoperative CRI. Avoid human
exposure when handling. Potential
for human abuse.
Ferrous sulfate (Fer-In-Sol, Iron-deficiency anemia: Iron-deficiency anemia: GI upset is common but can be lessened Tablets, oral solution; give
Feosol) 100-300 mg/DOG PO q 24h 50-100 mg/CAT PO once by administration with food. Overdosage with food. OTC.
q 24h can be fatal.
Filgrastim (Neupogen) Neutropenia: 5 mcg/kg SQ q 24h Neutropenia: 5 mcg/kg SQ Occasionally, irritation at the injection Injection (concentrations
q 24h site may occur. Bone or variable)
musculoskeletal pain, splenomegaly
(including splenic rupture),
glomerulonephritis, capillary leak
syndrome, and hypotension have been
reported in humans. Antibody formation
may occur.
Finasteride (Proscar, Benign prostatic hypertrophy: Dosing in cats is not Adverse effects include GI upset and Tablets
Propecia) 0.1-1 mg/kg PO q 24h described. minor sexual side effects. Use with
caution in hepatic impairment.
Firocoxib (Previcox, Equioxx) Antiinflammatory/analgesic Not recommended for use Can cause GI upset, but serious gastric Tablets (give with food),
NSAID: 5 mg/kg PO q 24h in cats. ulcer/perforation is possible. Do chewable tablets,
not combine with other NSAIDs or injection
corticosteroids.
Fluconazole (Diflucan) Susceptible mycotic infection, Susceptible mycotic infection, GI upset, CNS, and skin effects can Tablet, powder for oral
including fungal cystitis: including fungal cystitis: occur. Multiple drug interactions. Not suspension, injection
5-10 mg/kg PO, IV q 12-24h 5-10 mg/kg PO, IV q effective for all fungal infection (e.g.,
12-24h not effective for aspergillosis).
CNS cryptococcosis:
50-100 mg/CAT PO, IV q 12h
Flucytosine (Ancobon) Generally not recommended for Life-threatening Adverse effects include GI upset, bone Capsules
use in dogs due to severe cryptococcosis: 25-50 mg/ marrow suppression, cutaneous
toxicity kg PO q 6h or 50-65 mg/ eruption and rash, oral ulceration,
For life-threatening kg PO q 8h. Must be increased hepatic enzymes, and
cryptococcosis: 50-75 mg/ administered with a polyene CNS effects in cats. Use with
kg PO q 8h (much lower or azole antifungal agent extreme caution if at all for renal
doses, 25 mg/kg, sometimes impairment, pre-existing bone
recommended). Must be marrow depression, or hematologic
administered with a polyene or diseases or in patients receiving
azole antifungal agent. other bone marrow suppressant
drugs.
Fludrocortisone (Florinef) Hypoadrenocorticism: Hypoadrenocorticism: Adverse effects are dose related and Tablets; give with food.
0.1 mg/5 kg or 0.01 mg/kg PO 0.05-0.1 mg/CAT PO q include PU/PD, hypertension, edema,
q 24h, adjusted according to 24h adjusted according to and hypokalemia. GI discomfort may
response response occur and can be lessened with
food.
Flumazenil (Romazicon) Reversal of benzodiazepines: Reversal of benzodiazepines: Adverse effects include injection site Injection
0.01 mg/kg IV and repeat q h 0.01 mg/kg IV and repeat q reactions, vomiting, cutaneous
if needed h if needed vasodilation, vertigo, ataxia, and blurred
vision; seizures and cardiac arrhythmias
have been reported in humans. Use
extreme caution in mixed overdoses as
rapid withdrawal of benzodiazepines
may precipitate seizures if used to
Drug Compendium
control epilepsy.

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