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1506  Stanozolol (Winstrol-V)                                                                          Taurine



            Generic Name (Brand                                                                Administration/
            Name, Synonyms)   Canine Dosages      Feline Dosages      Adverse Effects/Warnings  Availability
  VetBooks.ir  Stanozolol (Winstrol-V)  Anabolic steroid: 1-4 mg/DOG   Do not use in cats.  Contraindicated in pregnancy and   No longer available in the
                               PO q 12h
                                                                       breeding animals. Cats may suffer
                                                                                                United States. Compounding
                                                                       severe hepatotoxicity. Adverse
                                                                                                pharmacists may prepare
                                                                       effects include electrolyte imbalance,
                                                                       behavioral change, GI upset, and   oral dosage forms. CSS-III.
                                                                       hepatotoxicity.
            Streptozotocin    Insulinoma: 500 mg/m  infusion   Do not use in cats.  Use with extreme caution in patients   Injection. Cytotoxic,
                                           2
             (Streptozotocin, Zanosar)  preceded and followed by       with decreased renal, bone marrow,   NIOSH-listed hazardous
                               extensive IV fluid diuresis             or hepatic function. May cause   drug and should be
                                                                       permanent DM. Adverse effects are   prepared, administered, and
                                                                       typically GI upset and hepatotoxicity.   disposed of in accordance
                                                                       Myelosuppression may also occur.  with federal and local
                                                                                                requirements.
            Sucralfate (Carafate)  Esophageal/gastric protectant:   Esophageal/gastric protectant:   Generally well tolerated. Constipation   Tablets (can be dissolved
                               0.25-1 g/DOG PO q    0.25-0.5 g/CAT PO q 4-12h  or vomiting (cats) can occur. May   in water just before
                               4-12h; use suspension for               impair absorption of several oral   administration), oral
                               esophageal disease                      medications (separate dosing by 2   suspension; give on empty
                                                                       hours when possible).    stomach 30 minutes before
                                                                                                meals.
            Sulfadimethoxine/ormetoprim  Susceptible infections: 55 mg/  Do not use in cats.  Adverse effects include KCS, GI upset,   Tablets
             (Primor)          kg PO initially, then 27.5 mg/          blood dyscrasia, and hypersensitivity
                               kg PO q 24h                             reactions. Doberman pinschers are
                                                                       more susceptible to polyarthritis
                                                                       caused by sulfonamides; use with
                                                                       caution in this breed.
            Sulfamethoxazole/  Susceptible infections:   Susceptible infections:   Adverse effects include KCS, GI upset,   Tablets, oral suspension
             trimethoprim (TMS,   15-30 mg/kg PO q 12h;   15-30 mg/kg PO q 12-24h  blood dyscrasia, and hypersensitivity
             co-trimoxazole, Tribrissen)  higher dose for nocardiosis  reactions. Doberman pinschers are
                                                                       more susceptible to polyarthritis
                                                                       caused by sulfonamides; use with
                                                                       caution in this breed.
            Sulfasalazine (Azulfidine)  IBD: 20-50 mg/kg PO q 8-12h  IBD: 10-20 mg/kg PO q   Adverse effects include KCS, GI upset,   Tablets; give with food.
                              Adjunct therapy for vasculitis:   12-24h  blood dyscrasia, and hypersensitivity
                               20-40 mg/kg PO q 8h                     reactions. Doberman pinschers are
                                                                       more susceptible to polyarthritis
                                                                       caused by sulfonamides; use with
                                                                       caution in this breed.





           T


            Generic Name (Brand                                                                 Administration/
            Name, Synonyms)   Canine Dosages       Feline Dosages     Adverse Effects/Warnings  Availability
            Tacrolimus        Perianal fistulae or other   Use in cats is not described.  Avoid human contact. Well tolerated for   Topical ointment. Owner
                               immunologically mediated                 topical skin application.  must wear gloves and
                               skin disorder: Applied to site                                    avoid contact (increased
                               of affected skin (use gloves) q                                   risk for cancers in
                               12h initially, reducing frequency                                 humans).
                               once disease improves
            Tadalafil (Cialis)  Pulmonary hypertension: 2-3 mg/  Use in cats is not described.  Adverse effects are typically GI upset. Do  Tablets
                               kg PO q 24h; can be titrated up          not use concurrently with nitrates. Use
                                                                        with extreme caution in patients with
                                                                        resting hypotension, fluid depletion,
                                                                        severe left ventricular outflow
                                                                        obstruction, or autonomic dysfunction.
            Tamsulosin (Flomax)  Urethral relaxant: 0.01-0.2 mg/kg  Urethral relaxant: 0.004-  Sustained-release dosage forms   Sustained-release capsules
                               PO q 24h             0.006 mg/kg PO q 12-24h  make extrapolation to small animals
                                                                        difficult. Adverse effects may include
                                                                        hypotension.
            Taurine           DCM: 0.5-1 g/DOG PO q 8-12h   DCM: 250-500 mg/CAT PO   Well tolerated.  Tablets OTC
                               for dogs weighing <25 kg and   q 12h
                               1-2 g/DOG PO q 8-12h for dogs
                               weighing >25 kg

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