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Marbofloxacin (Zeniquin) Meglumine antimonite (Glucantime, N-methyl-glucamine antimoniate) 1491

Generic Name (Brand Administration/
Name, Synonyms) Canine Dosages Feline Dosages Adverse Effects/Warnings Availability
VetBooks.ir Marbofloxacin (Zeniquin) Susceptible infections: Susceptible infections: Well tolerated, but adverse Tablets, injection. Compounding
2.75-5.5 mg/kg PO or SQ
pharmacies may prepare
effects include GI distress, CNS
2.75-5.5 mg/kg PO q 24h
q 24h
stable oral suspensions.
stimulation, or hypersensitivity.
Leishmaniasis: 2 mg/kg PO q
growing animals because of
but can give with nondairy
24h for 28 days Consider benefit/risk in young, Give on an empty stomach,
damage to cartilage. May foods to minimize GI upset if
increase seizure risk. Does necessary.
not cause retinopathy in cats
at recommended dose. Use
with caution in hepatic or renal
insufficiency and dehydration.
Maropitant (Cerenia) Antiemetic: 1 mg/kg SQ or IV Antiemetic: 1 mg/kg PO, SQ, or Generally well tolerated. SQ Tablets (give on empty stomach),
(slow injection) or 2 mg/kg IV (over 1-2 minutes) injection can cause pain injection. Keep refrigerated
PO q 24h Prevention of vomiting with CKD: (refrigerate to minimize). May to minimize pain on injection.
Prevention of motion sickness: 4 mg/CAT PO q 24-48h cause myelosuppression in If given IV, solutions should
8 mg/kg PO 2 hours before puppies <11 weeks of age. Use be administered over 1-2
travel then q 24h up to 2 with caution in hepatic failure or minutes.
days with cardiovascular disease. Do
Adjunct antitussive not use in GI obstruction or acute
(controversial use): 2 mg/kg intoxications. Human caregivers
PO q 48h should wear gloves as maropitant
causes contact dermatitis in
many humans.
Mastinib (Masivet, Kinavet) Antineoplastic (especially mast Not recommended for use in Not FDA approved. Proteinuria and Not available in the United
cell tumor): 12.5 mg/kg PO cats. neutropenia are relevant adverse States.
q 24h events.
Meclizine (Bonine, Prophylaxis of vestibular Prophylaxis of vestibular Adverse effects include dry Tablets OTC
Dramamine II, Antivert) syndromes, motion sickness: syndromes: 6.25-12.5 mg/CAT mouth, dry eyes, tachycardia.
4 mg/kg or 25 mg/DOG PO PO q 24h Paradoxical CNS stimulation
q 24h has also occurred. Due
to its anticholinergic side
effects, meclizine should be
used cautiously in prostatic
hypertrophy, bladder neck
obstruction, severe cardiac
failure, glaucoma, or
pyeloduodenal obstruction.
Medetomidine (Domitor) Sedation/restraint: 0.005- Sedation/restraint: 0.02 mg/kg Adverse effects are dose related Injection
0.02 mg/kg (5-20 mcg/kg) (20 mcg/kg) IM and include bradycardia,
IM as a single agent depressed respiration,
hypothermia, urination, vomiting,
hyperglycemia, and pain on IM
injection. May increase ocular
pressure in dogs but not cats.
Medroxyprogesterone Alopecia X: 5-7 mg/kg SQ q 4 Adjunctive therapy to refractory Drug rarely used due to adverse Tablets, injection. Injections
acetate (Provera) weeks for 4 treatments urine marking in neutered event profile, including PU/PD, administered SQ should be
Long-term reproductive control: male cats: 5-20 mg/kg SQ or lethargy, endocrinopathy, and given in visually inconspicuous
2.5-3 mg/kg IM q 5 months IM 3-4× yearly pyometra. It may predispose area as it may cause
Long-term reproductive control: animals to DM and should not be permanent alopecia at the
2 mg/kg IM q 5 months used in diabetics. May suppress injection site.
adrenal function; treated animals
may require supplemental
corticosteroids in stressful
situations.
Meglumine antimonite Leishmaniasis: 100 mg/ Use in cats is not described. Use in renal, hepatic, or cardiac Not available in the United
(Glucantime, N-methyl- kg SQ q 24h for 4 weeks failure carries a higher risk of States. May be obtained
glucamine antimoniate) +/- allopurinol adverse effects, including the through Centers for Disease
risk of worsening renal function Control and Prevention or
through damage to renal tubules. imported from Europe.
Other adverse effects include
injection site reactions, lethargy,
GI effects, and elevated liver
enzymes.
Drug Compendium

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