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Pamidronate (Aredia) Pentoxifylline (PTX, Trental) 1499

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VetBooks.ir Generic Name (Brand Canine Dosages Feline Dosages Adverse Effects/Warnings Administration/
Availability
Name, Synonyms)
Pamidronate (Aredia) Refractory hypercalcemia: Refractory hypercalcemia: Adverse effects include electrolyte Injection. Must be diluted in
1.3-2.3 mg/kg (diluted 1.3-2.3 mg/kg (diluted in imbalance and nephrotoxicity, 150-250 mL saline and
in 150-250 mL of 0.9% 150-250 mL of 0.9% sodium especially if administered too rapidly. administered over 2-4 hours
sodium chloride and chloride and administered IV Use with caution in patients with for IV dosing.
administered IV over 2-4 over 2-4 hours) impaired renal function. Use with
hours). Can repeat as soon caution in young or growing animals
as 1 week prn (typically q and in those animals healing from
3-6 weeks). bone fracture.
Pancreatic enzymes Pancreatic insufficiency: 2-3 Pancreatic insufficiency: 1 2 -1 Do not administer PO without mixing Powder (preferred), tablets.
(Viokase, Pancrezyme) crushed tablets or 3 4 -2 crushed tablet or 1 4 - 3 4 in food as oromucosal damage can Crush tablets before mixing
teaspoonfuls of powder teaspoonful of powder with result. Clients should avoid inhaling with food. Mix either powder
with each meal immediately each meal immediately powder or getting in eyes. GI upset is or crushed tablets with
before feeding; incubation is before feeding; incubation is the major adverse effect. food to minimize oral or
not necessary not necessary. esophageal erosion.
Pantoprazole (Protonix) Proton pump inhibitor antacid: Proton pump inhibitor antacid: Generally well tolerated. Diarrhea may Injection for IV use only;
0.7-1 mg/kg IV slowly (over 0.7-1 mg/kg IV slowly (over occur. Hyperglycemia has also been administer IV slowly over 15
15 minutes) q 24h 15 minutes) q 24h reported. minutes.
Paroxetine (Paxil) Behavioral disorders: Behavioral disorders: 0.25- Do not administer to patients who have Tablets, oral suspension
0.5-3 mg/kg PO q 24h 1.25 mg/kg PO q 24h received MAO inhibitors within the
previous 14 days. Use with caution
in patients with seizure disorders
or severe cardiac, hepatic, or renal
disease. If used in these conditions,
dosages must be reduced. Adverse
effects include lethargy, salivation, GI
upset, anxiety, irritability, insomnia,
hyperactivity, or panting. In cats,
behavioral changes, anorexia,
constipation, and changes in
elimination patterns may occur.
Penicillamine: see
D-penicillamine
Penicillin G potassium or Susceptible infections: Susceptible infections: Penicillin is generally well tolerated. Injection for IV use only.
sodium (PfizerPen) 20,000-40,000 units/kg IV 20,000-40,000 units/kg IV Allergic reactions can occur. Large Administer slowly to avoid
or IM q 4-8h or IM q 4-8h IV doses of penicillin potassium electrolyte imbalances.
and sodium can cause electrolyte
imbalances. Physically incompatible
with many other drugs in solution.
Penicillin G procaine Susceptible infections: Susceptible infections: Generally well tolerated. Allergic Injectable suspension. Shake
(Wycillin) 20,000-40,000 units/kg IM, 20,000-40,000 units/kg IM, reactions may occur. Do not give IV. vigorously before use, and
SQ q 12-24h SQ q 12-24h May cause injection site reactions. never administer IV.
Pentobarbital (Nembutal) Anesthesia: 10-30 mg/kg IV Anesthesia: 10-30 mg/kg IV Adverse effects include respiratory Injection for IV use only.
slowly to effect slowly to effect depression, hypothermia, and Avoid extravasation. When
Seizures: 3-15 mg/kg IV Seizures: 3-15 mg/kg IV slowly postanesthetic hyperexcitation. giving IV for induction of
slowly to effect to effect Contraindicated in severe liver anesthesia, administer 1 3
disease, nephritis, or respiratory to 1 2 of dose as bolus
depression. Use with caution followed by slow infusion
in hypovolemia, anemia, of the remainder to effect.
hypoadrenocorticism, or cardiac Expensive. CSS-II.
disease.
Pentosan polysulfate (PPS, Chondroprotective: 3 mg/kg Chondroprotective: 3 mg/kg Generally well tolerated, but GI upset is Injection. Not approved in the
Cartrophen-Vet, Elmiron) SQ or IM once weekly for SQ or IM once weekly for 4 reported. Mild anticoagulant effects. United States but can be
4 weeks weeks Contraindicated in advanced liver imported.
or kidney impairment, evidence
of infection, blood or coagulation
disorders, or malignancy. Avoid
several days before planned surgery.
Pentoxifylline (PTX, Trental) Inflammatory dermatoses or Inflammatory dermatoses or Well tolerated, but GI upset and CNS Tablets
vasculitis: 15-25 mg/kg PO vasculitis: 100 mg/CAT PO stimulation can occur. Use with
q 8-12h or 30 mg/kg PO q 12h caution in severe hepatic or renal
q 12h impairment and in patients at risk for
hemorrhage. Drug Compendium

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